HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyclopenten-1-one → ethyl 2-[3-[(1R)-3-oxocyclopentyl]-5-(trifluoromethyl)phenoxy]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyclopenten-1-one | HCID 13588 | — |
| Reactant | [3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-phenoxy]-acetic acid ethyl ester | HCID 68790116 | — |
| Catalyst | Tetrafluoroborate | HCID 26255 | — |
| Product | ethyl 2-[3-[(1R)-3-oxocyclopentyl]-5-(trifluoromethyl)phenoxy]acetate | HCID 49834558 | — |
Reaction Steps
The title compound was prepared from [3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-phenoxy]-acetic acid ethyl ester and 2-cyclopenten-1-one with Rh(R-BINAP)(nbd)]BF4 as catalyst in a manner similar to the one described for Preparation 6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785494B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-e9e0101b740944f5afafb60d79a76b59 |
| Source note | uspto-grants-2014_07 |