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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1627527Generated: October 27, 2026

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid → 6-Amino-5-benzyloxy-nicotinic acid

https://huagongshe.com/reaction/1627527

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acidHCID 2734621—
Reactant3-(Benzyloxy)-5-bromopyridin-2-amineHCID 20626554—
Product6-Amino-5-benzyloxy-nicotinic acidHCID 21111502—

Reaction Steps

6-Amino-5-benzyloxy-nicotinic acid was prepared according to procedure 3 from 3-benzyloxy-5-bromo-pyridin-2-ylamine and 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoic acid. MS m/z 321 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08785632B2
Source datasetuspto-grants-2014_07
ORD IDord-3bbb8c2ba8dc43939b1c9407f36f5056
Source noteuspto-grants-2014_07