HRID1627531

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21111491

未命名化合物

结构：CCN(CC)CCS(=O)(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1

HCID58886021

2-(Diethylamino)-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanesulfonamide

C18H31BN2O4S

PRODUCTS

生成物

结构：CCN(CC)CCS(=O)(=O)Nc1ccc(-c2cnc(N)c(OCc3c(F)ccc(F)c3Cl)c2)cc1

HCID58885829

未命名化合物

收率 60%

PROCEDURE

实验过程

2-diethylamino-ethanesulfonic acid {4-[6-amino-5-(2-chloro-3,6-difluoro-benzyloxy)-pyridin-3-yl]-phenyl}-amide was prepared following the general Suzuki coupling procedure 3 from 5-bromo-3-(2-chloro-3,6-difluoro-benzyloxy)-pyridin-2-ylamine and 2-diethylamino-ethanesulfonic acid [4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amide prepared in part 2 as a white solid in 60% yield.