Methanol → tert-Butyl 4-(6-amino-5-fluoro-1-oxoisoindolin-2-yl)piperidine-1-carboxylate
Reaction equation
[CH3:28][OH:29].[F:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][c:10]1[N+:11]([O-:12])=[O:13])[C:7](=[O:14])[N:6]([CH:15]1[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]1)[CH2:5]2>>[F:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][c:10]1[NH2:11])[C:7](=[O:14])[N:6]([CH:15]1[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]1)[CH2:5]2Participants
3
Sources & evidence
- ORD record
- ord-83bd9f118b034c3096cd5bd340eff913
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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