HCID 53212388, compound → HCID 136378631, compound

HRID 1627700Notes

Reaction equation

HRID 1627700 reaction equation
ClC1N=CC2C(=CC=C(O)C=2)N=1.[Cl:13][C:14]1[C:23]([C:24]([F:27])([F:26])[F:25])=[N:22][C:21]2[C:16](=[CH:17][CH:18]=[C:19]([O:28]C)[CH:20]=2)[N:15]=1>>[Cl:13][C:14]1[C:23]([C:24]([F:26])([F:27])[F:25])=[N:22][C:21]2[C:16](=[CH:17][CH:18]=[C:19]([OH:28])[CH:20]=2)[N:15]=1

Participants

3

Reactant 2

HCID 53212388HCID 53212388, compound2×HCID 593252542-Chloro-6-quinazolinol

Product 1

HCID 136378631HCID 136378631, compound

Procedure

Followed the procedure described for preparing Intermediate 10 starting with 2-chloro-6-methoxy-3-(trifluoromethyl)quinoxaline (Intermediate 11), with a purification by silica gel column chromatography.

Sources & evidence

ORD record
ord-32d6f26fdca049eea8e5ca1eef01fa6a
Source dataset
uspto-grants-2014_07
Patent number
US08785643B2

Reaction notes

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