Dimethylformamide → HCID 66597223, compound

Participants

Reaction Steps

This compound was prepared according to the procedure B from (2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-yl)-(p-tolyl)-methanone (0.546 g; 2 mmol), methyl levunilate (0.282 mL; 2.2 mmol), chlorotrimethylsilane (1 mL; 8 mmol) in DMF (8 mL) for 22 h. Purification by flash chromatography on silica gel using a gradient of ethyl acetate (2-80%) in heptane furnished 0.270 g (36%) of the title compound as a yellow solid.

Provenance & Evidence