Methanol → HCID 66597425, compound

HRID 1627939Notes

Reaction equation

HRID 1627939 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7]2[S:9][C:10]3[CH2:15][CH2:14][CH2:13][CH2:12][C:11]=3[C:6]2=[C:5]([C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=2)[C:4]=1[CH2:23][C:24]([OH:26])=[O:25].S(=O)(=O)(O)O.[CH3:32]O>>[CH3:1][O:2][C:3]1[N:8]=[C:7]2[S:9][C:10]3[CH2:15][CH2:14][CH2:13][CH2:12][C:11]=3[C:6]2=[C:5]([C:16]2[CH:17]=[CH:18][C:19]([CH3:22])=[CH:20][CH:21]=2)[C:4]=1[CH2:23][C:24]([O:26][CH3:32])=[O:25]

Participants

4

Reactant 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 49806221HCID 49806221, compound

Product 1

HCID 66597425HCID 66597425, compound

Procedure

The compound is prepared from the [2-methoxy-4-(p-tolyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridin-3-yl]acetic acid following standard esterification procedures known to the skilled in the art. As an example, the transformation is achieved using a catalytic amount of sulphuric acid in methanol.

Sources & evidence

ORD record
ord-f84c4d4bafa14ad088169b79169a2832
Source dataset
uspto-grants-2014_07
Patent number
US08785638B2

Reaction notes

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