tert-Butyl acrylate → HCID 58288941, compound

HRID 1627943Notes

Reaction equation

HRID 1627943 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH:9]=[CH2:10].[C:11]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])(=[O:14])C=C>>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1/[CH:9]=[CH:10]/[C:11]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14]

Participants

3

Reactant 2

HCID 15458tert-Butyl acrylateHCID 166942,4-Dimethylstyrene

Product 1

HCID 58288941HCID 58288941, compoundYield 74%

Procedure

The representative procedure was followed using 2,4-dimethyl-1-vinylbenzene (66 mg, 0.50 mmol), tert-butyl acrylate (128 mg, 1.00 mmol) and Grubbs-2 catalyst (8.5 mg, 0.01 mmol). Column chromatography on silica gel (eluting with 2% EtOAc/hexanes) afforded the product as a colorless oil (86 mg, 74%).

Sources & evidence

ORD record
ord-3018a48b67d94d6eb6fe7bdc15d396a7
Source dataset
uspto-grants-2014_07
Patent number
US08785665B2

Reaction notes

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