Cinnamyloxybenzene → (E)-N-Benzyl-N-(3-phenyl-2-propenyl)-3-phenylalanine ethyl ester

Participants

Reaction Steps

Following the general procedure using cinnamyloxybenzene (105 mg, 0.50 mmol) and ethyl 2-(benzylamino)-3-phenylpropanoate (212 mg, 0.75 mmol), the reaction was stirred for 2.5 h at rt. Column chromatography on silica gel (eluting with 10% EtOAc/hexanes) afforded the product as a pale yellow liquid (190 mg, 95%).

Provenance & Evidence