Hydrochloric Acid → HCID 67497636, compound

Participants

Reaction Steps

To a solution of tert-butyl (S)-1-(3-(1H-pyrazol-4-yl)phenylamino)-1-oxo-3-phenylpropan-2-ylcarbamate 13.E (1.25 g, 2.39 mmol) in MeOH (10 mL) was added 4M HCl in dioxane solution (10 ml, 40 mmol). The resulting mixture was stirred for 2 hours at room temperature. The mixture was then concentrated to afford crude (S)-2-amino-N-(2-(benzyloxy)-5-(pyridin-4-yl)phenyl)-3-phenylpropanamide 13.F which was used in the next step without any further purification.

Provenance & Evidence