HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-chloro-5-nitrobenzene → 3-Bromo-5-chloroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-chloro-5-nitrobenzene | HCID 17839838 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Bromo-5-chloroaniline | HCID 3084709 | 99.6% |
Reaction Steps
1-bromo-3-chloro-5-nitrobenzene (4.27 g, 18.0 mmol) was dissolved in acetic acid (24.1 mL μl, 18.0 mmol) then zinc dust (11.82 g, 180 mmol) was added. After 4 h the reaction was filtered and concentrated to afford 3-bromo-5-chlorobenzenamine (3.7 g, 99% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785468B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-12fc8808669d4aca9dc5798bbb8edda5 |
| Source note | uspto-grants-2014_07 |