HCID 67496690, compound → HCID 69620893, compound

HRID 1628295Notes

Reaction equation

HRID 1628295 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:9]=[C:10]([NH2:15])[CH:11]=[C:12]([NH2:14])[CH:13]=2)[CH:5]=[CH:4][N:3]=1.[O:16]=[C:17](NC1N=C(C2C=CN=CC=2)SC=1)[C@@H:18]([NH:26][C:27](=[O:33])[O:28][C:29]([CH3:32])([CH3:31])[CH3:30])[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[NH2:14][C:12]1[CH:11]=[C:10]([NH:15][C:17](=[O:16])[C@@H:18]([NH:26][C:27](=[O:33])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:9]=[C:8]([C:6]2[CH:5]=[CH:4][N:3]=[C:2]([CH3:1])[CH:7]=2)[CH:13]=1

Participants

3

Reactant 2

HCID 67496690HCID 67496690, compoundHCID 69620697HCID 69620697, compound

Product 1

HCID 69620893HCID 69620893, compound

Procedure

This title compound was prepared from 51.1C (2.10 g, 10.0 mmol) according the procedure described above for conversion of 4.A to 4.B. The product 51.1D was purified by flash chromatography on silica gel using 0-7% MeOH/CH2Cl2 for elution.

Workup

  1. customThe product 51.1D was purified by flash chromatography on silica gel using 0-7% MeOH/CH2Cl2 for elution

Sources & evidence

ORD record
ord-8000ae479a6e40e5a413901779709bcc
Source dataset
uspto-grants-2014_07
Patent number
US08785468B2

Reaction notes

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