HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → HCID 67497053, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | HCID 68759365 | HCID 68759365 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67497053 | HCID 67497053 | 75.6% |
Reaction Steps
To (S)-methyl 1-(2-(tert-butoxycarbonyl)-3-phenylpropanoyl)-6-(pyridin-4-yl)indoline-4-carboxylate 58.A (339 mg, 0.68 mmol, prepared as in example 54.1) was added 4 mL EtOH and hydrazine (0.3 mL, 0.96 mmol). The reaction was refluxed overnight and concentrated. Silica gel purification afforded 250 mg (74%) product 58.B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785468B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-9db94e85b4de436aa9e20802b0ac2c51 |
| Source note | uspto-grants-2014_07 |