Tetrahydrofuran → HCID 21915845, compound

Participants

Reaction Conditions

Reaction Steps

3.33 g (0.01289 mol) of [1,1′;3′,1″]terphenyl-5′-carbaldehyde are dissolved in 12 ml of THF and added to methyltriphenylphosphonium bromide solution. The yellowish mixture is stirred at 0° C. for 1 h. After cooling to room temperature, the mixture is taken up in dichloromethane. The solution is washed with water, and the combined organic phases are dried over sodium sulfate. The mixture is evaporated to dryness. Column chromatography is carried out with hexane/ethyl acetate. The column chromatography results in a yield of 2.4 g (71%) of clean substance.

Provenance & Evidence