反应详情

1.21 g (0.0091 mol) of aluminium chloride, 1.997 g (0.0091 mol) of 4-bromobenzoyl chloride and 3.42 g (0.01911 mol) of 4-cyanobiphenyl are initially introduced. The solids are dissolved in 80 ml of 1,2-dichlorobenzene. 0.2 ml (0.00274 mol) of thionyl chloride is added. The reaction is carried out at 120° C. for 24 h. After a reaction time of 1 h, 0.9736 g (0.00182 mol) of ammonium chloride is added. As work-up, the mixture is poured into 50 ml of methanol. The white solid is filtered off with suction and recrystallised in chloroform/ethanol. 1.7 g (34%) of clean substance are isolated.

1. filtrationThe white solid is filtered off with suction
2. customrecrystallised in chloroform/ethanol
3. custom1.7 g (34%) of clean substance are isolated