5-{4-(3-Chlorophenyl)-2-[(4-oxoimidazolidin-1-yl)carbonyl]-1,3-thiazole-5-yl}-2-fluorobenzenecarbonitrile → 3-{4-(3-Chlorophenyl)-2-[(4-oxoimidazolidin-1-yl)carbonyl]-1,3-thiazole-5-yl}benzenecarbonitrile

HRID 162867Notes

Reaction equation

HRID 162867 reaction equation
[Br:30][c:31]1[s:32][c:33]([C:34]([N:35]2[CH2:36][C:37](=[O:38])[NH:39][CH2:40]2)=[O:41])[n:42][c:43]1-[c:44]1[cH:45][cH:46][c:47]([F:48])[c:49]([Cl:50])[cH:51]1.[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]([C:22](=[O:23])[N:24]3[CH2:25][NH:26][C:27](=[O:29])[CH2:28]3)[s:11][c:12]2-[c:13]2[cH:14][cH:15][c:16]([F:21])[c:17]([C:19]#[N:20])[cH:18]2)[cH:5][cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]([C:22](=[O:23])[N:24]3[CH2:25][NH:26][C:27](=[O:29])[CH2:28]3)[s:11][c:12]2-[c:13]2[cH:14][cH:15][cH:16][c:17]([C:19]#[N:20])[cH:18]2)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 703152005-{4-(3-Chlorophenyl)-2-[(4-oxoimidazolidin-1-yl)carbonyl]-1,3-thiazole-5-yl}-2-fluorobenzenecarbonitrileHCID 708015141-{[5-Bromo-4-(3-chloro-4-fluorophenyl)-1,3-thiazole-2-yl]carbonyl}imidazolidin-4-one

Product 1

HCID 509429183-{4-(3-Chlorophenyl)-2-[(4-oxoimidazolidin-1-yl)carbonyl]-1,3-thiazole-5-yl}benzenecarbonitrile

Sources & evidence

ORD record
ord-32fe7a91870e4f038a6fd53ace94c41a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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