Hexachloroethane → 5-Chloro-1-(2-chloro-phenyl)-1H-[1,2,4]triazole

Participants

Role	Name	HCID	Charge
Reactant	Hexachloroethane	HCID 6214	—
Reactant	1-(2-chloro-phenyl)-1H-[1,2,4]triazole	HCID 23162872	—
Reactant	5-chloro-1-(2,4-difluoro-phenyl)-1H-[1,2,4]triazole	HCID 58204986	—
Reactant	Butyllithium	HCID 178418339	—
Product	5-Chloro-1-(2-chloro-phenyl)-1H-[1,2,4]triazole	HCID 58204441	—

Reaction Steps

Following the procedure for 5-chloro-1-(2,4-difluoro-phenyl)-1H-[1,2,4]triazole, 1-(2-chloro-phenyl)-1H-[1,2,4]triazole was reacted with n-butyllithium and hexachloroethane to give 5-Chloro-1-(2-chloro-phenyl)-1H-[1,2,4]triazole as a white solid. 1H NMR δ (ppm)(CDCl3): 8.05 (1 H, s), 7.61-7.58 (1 H, m), 7.55-7.48 (1 H, m), 7.46-7.43 (2 H, m).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08785626B2
Source dataset	uspto-grants-2014_07
ORD ID	ord-669f4ca1a8fb4266ba4835a7c11ba3da
Source note	uspto-grants-2014_07