6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid → 6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amide

HRID 162956Notes

Reaction equation

HRID 162956 reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:20])([F:21])[CH2:18][CH2:19]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[NH2:22][C:23]([C:24](=[O:25])[NH:26][CH3:27])([CH2:28][CH3:29])[CH2:30][CH3:31]>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:20])([F:21])[CH2:18][CH2:19]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:22][C:23]([C:24](=[O:25])[NH:26][CH3:27])([CH2:28][CH3:29])[CH2:30][CH3:31])[n:11]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 710877506-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acidHCID 798103702-Amino-2-ethyl-N-methyl-butyramide

Product 1

HCID 710936046-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amide

Sources & evidence

ORD record
ord-3bf8fb91f7804412b967634262283d15
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…