HCID 53724788, compound → HCID 86685857, compound

HRID 1629766Notes

Reaction equation

HRID 1629766 reaction equation
[F:1][C:2]([F:20])([F:19])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][CH2:14][C:15](F)(F)F)=[CH:7][CH:6]=1)=[O:4].[F:21][C:22]([F:36])([F:35])[CH2:23]CCOC1C=CC(C=O)=CC=1.FC(F)(F)CCCCCOC1C=CC(C=O)=CC=1>>[F:1][C:2]([F:20])([F:19])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:23][C:22]([F:36])([F:35])[F:21])=[CH:7][CH:6]=1)=[O:4]

Participants

4

Reactant 3

HCID 53724788HCID 53724788, compoundHCID 86685848HCID 86685848, compoundHCID 86685856HCID 86685856, compound

Product 1

HCID 86685857HCID 86685857, compound

Procedure

Intermediate 8B was prepared using a procedure analogous to Intermediate 2C except that Intermediate 2A was replaced with Intermediate 8A. 1H NMR (500 MHz, CDCl3) δ 8.06-8.02 (m, 2H), 6.99-6.97 (m, 1H), 4.08 (t, J=6.2 Hz, 2H), 2.19-2.06 (m, 2H), 1.92-1.82 (m, 2H), 1.71-1.55 (m, 4H).

Sources & evidence

ORD record
ord-484503444b334d209d1a16804e59e7ad
Source dataset
uspto-grants-2014_07
Patent number
US08791091B2

Reaction notes

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