Acetic Acid → (3-{4-[(6-Cyano-pyridin-2-ylmethyl)-amino]-piperidin-1-yl}-butyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH:10]([CH3:11])[N:12]1[CH2:13][CH2:14][C:15](=[O:18])[CH2:16][CH2:17]1)=[O:19].[C:30]([O:31][BH-:32]([O:33][C:34](=[O:35])[CH3:36])[O:37][C:38](=[O:39])[CH3:40])(=[O:41])[CH3:42].[CH3:44][C:45](=[O:46])[OH:47].[Cl:48][CH2:49][Cl:50].[NH2:20][CH2:21][c:22]1[cH:23][cH:24][cH:25][c:26]([C:28]#[N:29])[n:27]1.[Na+:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH:10]([CH3:11])[N:12]1[CH2:13][CH2:14][CH:15]([NH:20][CH2:21][c:22]2[cH:23][cH:24][cH:25][c:26]([C:28]#[N:29])[n:27]2)[CH2:16][CH2:17]1)=[O:19]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c261c2879db84f609c2c7345a940f796
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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