HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylhomopiperazine → HCID 54934279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylhomopiperazine | HCID 228349 | — |
| Reactant | 4-Fluoro-3-methylbenzonitrile | HCID 2779180 | — |
| Product | HCID 54934279 | HCID 54934279 | — |
Reaction Steps
7.00 g (51.8 mmol) 4-fluoro-3-methyl-benzonitrile are heated to 110° C. together with 1-N-methyl-[1,4]diazepan for 1 week with stirring. After evaporation i. vac. the residue is separated on aluminium oxide (eluant: dichloromethane) and the corresponding fractions are again purified on silica gel (eluting gradient: dichloromethane/methanol 100:1->9:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791103B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-e5bc2013a0de4c758742dc1e44d48ac0 |
| Source note | uspto-grants-2014_07 |