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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1629903Generated: October 31, 2026

Lithium Hydroxide → 3-Chloro-4-(5-methyl-morpholin-3-on-4-yl)-benzoic acid

https://huagongshe.com/reaction/1629903

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantEthyl 3-chloro-4-(5-methyl-morpholin-3-on-4-yl)-benzoateHCID 67049237—
SolventWaterHCID 962—
SolventTetrahydrofuranHCID 8028—
Product3-Chloro-4-(5-methyl-morpholin-3-on-4-yl)-benzoic acidHCID 67048505—

Reaction Steps

Prepared analogously to Example 31b from ethyl 3-chloro-4-(5-methyl-morpholin-3-on-4-yl)-benzoate with lithium hydroxide in THF and water.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791103B2
Source datasetuspto-grants-2014_07
ORD IDord-afa73af2345e483a93ab13c936325c26
Source noteuspto-grants-2014_07