Ethanol → HCID 63174906, compound

HRID 1629906Notes

Reaction equation

HRID 1629906 reaction equation
[Cl:1][C:2]1[CH:3]=C([CH:7]=[CH:8][C:9]=1[N:10]1[CH2:14][CH2:13][CH:12]([N:15]([CH3:17])[CH3:16])[CH2:11]1)C#N.[OH-:18].[Na+].[CH2:20]([OH:22])[CH3:21]>>[Cl:1][C:2]1[CH:3]=[C:21]([CH:7]=[CH:8][C:9]=1[N:10]1[CH2:14][CH2:13][CH:12]([N:15]([CH3:17])[CH3:16])[CH2:11]1)[C:20]([OH:18])=[O:22]

Participants

4

Reactant 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 63512177HCID 63512177, compound

Product 1

HCID 63174906HCID 63174906, compound

Procedure

Prepared analogously to Example 13b from 3-chloro-4-(3-dimethylamino-pyrrolidin-1-yl)-benzonitrile with 10-molar sodium hydroxide solution and ethanol.

Sources & evidence

ORD record
ord-f1518f8bfdb148d298a95081a74f62f0
Source dataset
uspto-grants-2014_07
Patent number
US08791103B2

Reaction notes

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