HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- → (S)-2-amino-3-(benzyloxy)-N-(4-(4-methoxyphenoxy)phenyl)propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- | HCID 90234 | — |
| Reactant | 4-(4-Methoxyphenoxy)aniline | HCID 101402 | — |
| Product | (S)-2-amino-3-(benzyloxy)-N-(4-(4-methoxyphenoxy)phenyl)propanamide | HCID 67010093 | 90% |
Reaction Steps
Proceeding as in Reference 5, but substituting 4-(4-methoxyphenoxy)aniline and (S)-3-(benzyloxy)-2-(tert-butoxycarbonylamino)propanoic acid, gave (S)-2-amino-3-(benzyloxy)-N-(4-(4-methoxyphenoxy)phenyl)propanamide (710 mg, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791102B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-ef2937cacc4546b18551d4b0130012ab |
| Source note | uspto-grants-2014_07 |