HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenamine, 4-(4-fluorophenoxy)- → (S)-2-amino-3-(4-fluorobenzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenamine, 4-(4-fluorophenoxy)- | HCID 147633 | — |
| Reactant | (S)-2-(tert-butoxycarbonylamino)-3-(4-fluorobenzyloxy)propanoic acid | HCID 54280348 | — |
| Product | (S)-2-amino-3-(4-fluorobenzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide | HCID 67009398 | 84% |
Reaction Steps
Proceeding as in Reference 5, but substituting 4-(4-fluorophenoxy)aniline and (S)-2-(tert-butoxycarbonylamino)-3-(4-fluorobenzyloxy)propanoic acid, gave (S)-2-amino-3-(4-fluorobenzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide (200 mg, 84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791102B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-7593ad3adaf541da9ffeff25b1a03af2 |
| Source note | uspto-grants-2014_07 |