HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Bromophenoxy)aniline → (S)-2-amino-N-(4-(4-bromophenoxy)phenyl)-3-(4-fluorobenzyloxy)propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Bromophenoxy)aniline | HCID 759367 | — |
| Reactant | (S)-2-(tert-butoxycarbonylamino)-3-(4-fluorobenzyloxy)propanoic acid | HCID 54280348 | — |
| Product | (S)-2-amino-N-(4-(4-bromophenoxy)phenyl)-3-(4-fluorobenzyloxy)propanamide | HCID 67010031 | 50% |
Reaction Steps
Proceeding as in Reference 5, but substituting 4-(4-bromophenoxy)aniline and (S)-2-(tert-butoxycarbonylamino)-3-(4-fluorobenzyloxy)propanoic acid, gave (S)-2-amino-N-(4-(4-bromophenoxy)phenyl)-3-(4-fluorobenzyloxy)propanamide (200 mg, 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791102B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-33f35ecbedbb4098bf083bf7b8fb30bf |
| Source note | uspto-grants-2014_07 |