huagongshe.com
HRID1630083

反应详情

EQUATION

反应方程式

HRID 1630083 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)Cn1cncn1
HCID1810180

1,2,4-Triazole-1-acetic acid

C4H5N3O2

结构：CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1
HCID67010572

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](O)CN1C(=O)Cn1cncn1
HCID56953686

未命名化合物

PROCEDURE

实验过程

Proceeding as in Reference 11, but substituting 2-(1H-1,2,4-triazol-1-yl)acetic acid and (2S,4R)-tert-butyl 2-(4-(4-fluorophenoxy)phenylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate, gave (2S,4R)-1-(2-(1H-1,2,4-triazol-1-yl)acetyl)-N-(4-(4-fluorophenoxy)phenyl)-4-hydroxypyrrolidine-2-carboxamide.