HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,4-Triazole-1-acetic acid → HCID 67009741, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,4-Triazole-1-acetic acid | HCID 1810180 | — |
| Reactant | HCID 67010056 | HCID 67010056 | — |
| Product | HCID 67009741 | HCID 67009741 | 70% |
Reaction Steps
Proceeding as in Reference 11, but substituting (2R,4R)—N-(4-(4-fluorophenoxy)phenyl)-4-hydroxypyrrolidine-2-carboxamide and 2-(1H-1,2,4-triazol-1-yl)acetic acid gave (2R,4R)-1-(2-(1H-1,2,4-triazol-1-yl)acetyl)-N-(4-(4-fluorophenoxy)phenyl)-4-hydroxypyrrolidine-2-carboxamide (1.37 g, 3.25 mmol, 70% yield) as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791102B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-759e787173304fc4a1e3fac7771b7e5e |
| Source note | uspto-grants-2014_07 |