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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1630154Generated: November 2, 2026

(S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide → HCID 67009828, compound

https://huagongshe.com/reaction/1630154

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamideHCID 67009137—
ReactantHCID 86659470HCID 86659470—
ProductHCID 67009828HCID 6700982853.8%

Reaction Steps

Proceeding as in Example 1, but substituting 3-methylbutanoic acid hydrochloride and (S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide, gave Compound 233, (S)—N-(3-(benzyloxy)-1-(4-(4-fluorophenoxy)phenylamino)-1-oxopropan-2-yl)-3-methylbutanamide (3 mg, 53.8%). MS (EI) for C27H29FN2O4. found 465.5 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791102B2
Source datasetuspto-grants-2014_07
ORD IDord-17802dac5265440680ac9f1dfc3938ed
Source noteuspto-grants-2014_07