HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridineacetic acid, hydrochloride (1:1) → HCID 67010683, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridineacetic acid, hydrochloride (1:1) | HCID 2723724 | — |
| Reactant | (S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide | HCID 67009137 | — |
| Product | HCID 67010683 | HCID 67010683 | 50% |
Reaction Steps
Proceeding as in Example 1, but substituting 2-(pyridin-3-yl)acetic acid hydrochloride and (S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide, gave Compound 247, (S)-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)-2-(2-(pyridin-3-yl)acetamido)propanamide (3 mg, 50%). MS (EI) for C29H26FN3O4. found 500.5 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791102B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-5af7d7e41abf47e5a222dbfb631ec2e6 |
| Source note | uspto-grants-2014_07 |