HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide → HCID 67010479, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide | HCID 67009137 | — |
| Reactant | HCID 67009784 | HCID 67009784 | — |
| Product | HCID 67010479 | HCID 67010479 | 42.8% |
Reaction Steps
Proceeding as in Example 1, but substituting 2-(3-fluoro-4-(trifluoromethyl)phenyl)acetic acid hydrochloride and (S)-2-amino-3-(benzyloxy)-N-(4-(4-fluorophenoxy)phenyl)propanamide, gave Compound 101, (S)-3-(benzyloxy)-2-(2-(3-fluoro-4-(trifluoromethyl)phenyl)acetamido)-N-(4-(4-fluorophenoxy)phenyl)propanamide (3 mg, 42.8%). MS (EI) for C31H25F5N2O4. found 585.5 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791102B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-841b5b627fe24b34aea0cc69665c92bf |
| Source note | uspto-grants-2014_07 |