HCID 60208666, compound → HCID 67009276, compound

Participants

Reaction Steps

Proceeding as in Example 1, but substituting 2-phenylacetic acid hydrochloride and (2S,4R)-4-benzyl-N-(4-(4-fluorophenoxy)phenyl)pyrrolidine-2-carboxamide, gave Compound 31, (2S,4R)-4-benzyl-N-(4-(4-fluorophenoxy)phenyl)-1-(2-phenylacetyl)pyrrolidine-2-carboxamide (13.4 mg, 43.9%). 1H-NMR (400 MHz, DMSO-D6): σ 9.97 (s, 1H), 7.54 (t, 2H), 7.19 (m, 12H), 6.97 (m, 4H), 3.74 (m, 1H), 3.65 (s, 2H), 3.27 (m, 2H), 2.62 (m, 4H). MS (EI) for C32H29FN2O3: 509.6 (MH+).

Provenance & Evidence