Benzene, 1-fluoro-2-methyl-4-nitro- → 1-(2-Hydroxyethyl)-4-(2-methyl-4-nitrophenyl)piperazine

Participants

Reaction Steps

In the same manner as in Production Example 5-1, but using 4-(2-ethoxyethyl)piperazine in place of N-ethylpiperazine used in Production Example 5-1, using 5-nitro-2-fluorotoluene in place of 2-fluoro-5-nitrobenzyl alcohol, using N,N-diisopropylethylamine in place of potassium carbonate, and using dimethylsulfoxide in place of N-methylpyrrolidone, the entitled compound was obtained as a yellow solid.

Provenance & Evidence