化工社化工社 化学情報印刷レポート · 研究参考用
2,4-Difluorobenzoic acid → 1-Methyl-4-nitrosopiperidin-4-yl 2,4-difluorobenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,4-Difluorobenzoic acid | HCID 74102 | — |
| 反応物 | 1-Methylpiperidin-4-one oxime | HCID 339053 | — |
| 反応物 | HCID 178418268 | HCID 178418268 | — |
| 生成物 | 1-Methyl-4-nitrosopiperidin-4-yl 2,4-difluorobenzoate | HCID 57954497 | — |
反応手順
1-Methyl-4-nitrosopiperidin-4-yl 2,4-difluorobenzoate was prepared from 1-methyl-piperidin-4-one oxime, lead tetraacetate and 2,4-difluorobenzoic acid using conditions of General Method 3. 1H NMR (400 MHz, chloroform-d) δ 7.59 (2H, dd, 7.5, 2.3 Hz), 7.09 (1H, tt, 8.6, 2.4 Hz), 2.98 (2H, dt, 11.7, 3.6 Hz), 2.32-2.50 (7H, m), 2.04 (2H, dd, 14.2, 2.7 Hz).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08791134B2 |
| 出典データセット | uspto-grants-2014_07 |
| ORD ID | ord-6af5c64cb2064bb09f3da7c3a3672ff1 |
| 出典メモ | uspto-grants-2014_07 |