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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1630808Generated: October 26, 2026

Methyl 4-(2-bromoethoxy)benzoate → 4-[2-(5-Chloro-3-methyl-2-pyridin-3-yl-indol-1-yl)-ethoxy]-benzoic acid methyl ester

https://huagongshe.com/reaction/1630808

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(2-bromoethoxy)benzoateHCID 1898264—
Reactant5-chloro-3-methyl-2-pyridin-3-yl-1H-indole hydrochlorideHCID 44553962—
Product4-[2-(5-Chloro-3-methyl-2-pyridin-3-yl-indol-1-yl)-ethoxy]-benzoic acid methyl esterHCID 58215690—

Reaction Steps

4-(2-Bromo-ethoxy)-benzoic acid methyl ester (Example 61a) and 5-chloro-3-methyl-2-pyridin-3-yl-indol-1-yl (Example 2) are processed according to the method described in Example 59 to give 4-[2-(5-chloro-3-methyl-2-pyridin-3-yl-indol-1-yl)-ethoxy]-benzoic acid methyl ester. MS (ESI) m/z 421.01.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791141B2
Source datasetuspto-grants-2014_07
ORD IDord-f2a5a69da5d840629c67fbb1edf48e3b
Source noteuspto-grants-2014_07