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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1630846Generated: October 31, 2026

3-Bromo-5-methylpyridine → 6-chloro-2-(5-methyl-pyridin-3-yl)-1H-indole

https://huagongshe.com/reaction/1630846

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-methylpyridineHCID 817713—
Reactant1-Boc-6-chloroindole-2-boronic acidHCID 44119151—
Product6-chloro-2-(5-methyl-pyridin-3-yl)-1H-indoleHCID 58215750—

Reaction Steps

3-Methyl-5-bromopyridine and N-Boc-6-chloro-indole-2-boronic acid are processed according to the procedure described in Example 91 to give 6-chloro-2-(5-methyl-pyridin-3-yl)-1H-indole. (ESI) m/z 243.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791141B2
Source datasetuspto-grants-2014_07
ORD IDord-7d29e7f78c3847da95ded60d7c9e2857
Source noteuspto-grants-2014_07