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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1630848Generated: October 31, 2026

3-Bromo-5-fluoropyridine → 5-fluoro-2-(5-fluoro-pyridin-3-yl)-1H-indole

https://huagongshe.com/reaction/1630848

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-fluoropyridineHCID 820206—
Reactant5-Fluoro-1H-indole-2-boronic acid, N-BOC protectedHCID 2763292—
Product5-fluoro-2-(5-fluoro-pyridin-3-yl)-1H-indoleHCID 58215640—

Reaction Steps

3-Fluoro-5-bromopyridine and N-Boc-5-fluoro-indole-2-boronic acid are processed according to the procedure described in Example 91 to give 5-fluoro-2-(5-fluoro-pyridin-3-yl)-1H-indole. (ESI) m/z 231.04 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791141B2
Source datasetuspto-grants-2014_07
ORD IDord-8f94f0f0b8a04835b945e053ac6e4c0c
Source noteuspto-grants-2014_07