HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-(+)-1-Boc-3-aminopyrrolidine → HCID 59534631, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-(+)-1-Boc-3-aminopyrrolidine | HCID 854070 | — |
| Reactant | 6-chloro-2-(5-formyl-pyridin-3-yl)-1-methyl-1H-indole-3-carbonitrile | HCID 58215771 | — |
| Product | HCID 59534631 | HCID 59534631 | — |
Reaction Steps
6-Chloro-2-(5-formyl-pyridin-3-yl)-1-methyl-1H-indole-3-carbonitrile (Example 126) and (R)-3-amino-pyrrolidine-1-carboxylic acid tert-butyl ester are processed according to the method described in Example 170 to give (R)-3-{[5-(6-chloro-3-cyano-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-amino}-pyrrolidine-1-carboxylic acid tert-butyl ester. MS (ESI) m/z 466.11 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791141B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-7086e91dc82a4e978f76e20a11ebe608 |
| Source note | uspto-grants-2014_07 |