Methyl 4-bromo-3-(methoxymethyl)benzoate → HCID 46909205, compound

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Reaction Steps

The title compound was prepared following procedure described in Method B starting from Intermediate A1 and N′-hydroxy-6-pyrrolidin-1-ylpyridine-3-carboximidamide (UkrOrgSynthesis, BBV-073346). After purification by flash chromatography (silica, EtOAc/cHex) followed by a crystallization from a mixture of MTBE and heptane, the title compound was obtained as an off-white powder. HPLC (Method A), Rt: 4.1 min (purity: 99%). UPLC/MS, M+(ESI): 417.1, M−(ESI): 415.2. Elemental analysis: [C26H26N4O2-0.2H20] calculated: C, 72.60%; H, 6.19%; N, 13.03%. found: C, 72.68%; H, 6.45%; N, 13.05%.

Provenance & Evidence