1-Benzofuran-2-sulfonyl chloride → HCID 178453007, compound

HRID 1631229Notes

Reaction equation

HRID 1631229 reaction equation
[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[NH:12][C:11]([CH2:13][S:14][C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:16]=2[NH2:22])=[N:10][N:9]=1)([CH3:4])([CH3:3])[CH3:2].[O:24]1[C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=2[CH:26]=[C:25]1[S:33](Cl)(=[O:35])=[O:34]>N1C=CC=CC=1>[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[NH:12][C:11]([CH2:13][S:14][C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:16]=2[NH:22][S:33]([C:25]2[O:24][C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=3[CH:26]=2)(=[O:34])=[O:35])=[N:10][N:9]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 27951721-Benzofuran-2-sulfonyl chlorideHCID 178453006HCID 178453006, compound

Product 1

HCID 178453007HCID 178453007, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Following General Procedure B, the title compound was prepared from tert-butyl(5-(((2-amino-4-chlorophenyl)thio)methyl)-4H-1,2,4-triazol-3-yl)carbamate (330 mg, 0.925 mmol) and benzofuran-2-sulfonyl chloride (200 mg, 0.925 mmol) in pyridine (2 ml).

Sources & evidence

ORD record
ord-410e42e30f6d415288b692e68ececdf0
Source dataset
uspto-grants-2014_07
Patent number
US08791161B2

Reaction notes

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