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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1631362Generated: November 4, 2026

Ammonia → HCID 67501506, compound

https://huagongshe.com/reaction/1631362

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 66847769HCID 66847769—
SolventMethanolHCID 887—
ProductHCID 67501506HCID 6750150638%

Reaction Steps

Prepared by the method described in Example 1 using (R)-5-(2-(5-fluoro-2-methoxypyridin-3-yl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (Preparation K) and 7N NH3 in MeOH. The combined organic extracts were concentrated and the residue was purified by reverse phase HPLC (0-80% acetonitrile/water) to provide the title compound (15 mg, 38% yield). MS (apci) m/z=357.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791123B2
Source datasetuspto-grants-2014_07
ORD IDord-ae28fd6311d34c998514c3b6908f05bf
Source noteuspto-grants-2014_07