4-(Trifluoromethylsulfonyl)benzaldehyde → 1-(broMoMethyl)-4-((trifluoroMethyl)sulfonyl)benzene

HRID 1631507Notes

Reaction equation

HRID 1631507 reaction equation
[Br:1]CC1C=CC(S(C)(=O)=O)=C(F)C=1.[F:14][C:15]([F:28])([F:27])[S:16]([C:19]1[CH:26]=[CH:25][C:22]([CH:23]=O)=[CH:21][CH:20]=1)(=[O:18])=[O:17]>>[Br:1][CH2:23][C:22]1[CH:25]=[CH:26][C:19]([S:16]([C:15]([F:28])([F:27])[F:14])(=[O:18])=[O:17])=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 41755934-(Trifluoromethylsulfonyl)benzaldehydeHCID 672190653-Fluoro-4-(methylsulphonyl)benzyl bromide

Product 1

HCID 153235981-(broMoMethyl)-4-((trifluoroMethyl)sulfonyl)benzene

Procedure

The titled compound is prepared analogously to 4-bromomethyl-2-fluoro-1-methanesulfonyl-benzene by replacing 3-fluoro-4-methanesulfonyl-benzaldehyde with 4-trifluoromethanesulfonyl-benzaldehyde.

Sources & evidence

ORD record
ord-dad7836f8d0d47d9a22f3771525fbdfa
Source dataset
uspto-grants-2014_07
Patent number
US08791256B2

Reaction notes

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