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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1631523Generated: October 26, 2026

4-Methoxy-3-nitrobenzonitrile → 5-Cyano-2-methoxybenzene-1-sulfonyl chloride

https://huagongshe.com/reaction/1631523

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxy-3-nitrobenzonitrileHCID 2800241—
Reactant4-Cyano-3-ethoxybenzene-1-sulfonyl chlorideHCID 55280879—
Product5-Cyano-2-methoxybenzene-1-sulfonyl chlorideHCID 11528751—

Reaction Steps

The titled compound was prepared analogously to 4-cyano-3-ethoxy-benzenesulfonyl chloride (Intermediate 127c) by replacing 2-ethoxy-4-nitro-benzonitrile with 4-methoxy-3-nitro-benzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791256B2
Source datasetuspto-grants-2014_07
ORD IDord-64cbe8db362648e6a8fe15029bc9bd73
Source noteuspto-grants-2014_07