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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1631561Generated: October 31, 2026

3-Fluoroaniline → HCID 136230226, compound

https://huagongshe.com/reaction/1631561

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FluoroanilineHCID 9742—
ReactantEthyl 2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetateHCID 135905419—
ProductHCID 136230226HCID 136230226—

Reaction Steps

The product is prepared according to the procedure described in Example 9, using 250 mg of ethyl [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate prepared in stage 1 of Example 1 and 0.90 ml of 3-fluoroaniline in place of the 2-fluoroaniline. 160 mg of N-(3-fluorophenyl)-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a white solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791255B2
Source datasetuspto-grants-2014_07
ORD IDord-49658880364940efb9e3596daf6a5804
Source noteuspto-grants-2014_07