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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1631575Generated: November 2, 2026

4-Fluoro-m-toluidine → HCID 136230232, compound

https://huagongshe.com/reaction/1631575

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-m-toluidineHCID 67981—
ReactantSodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetateHCID 136041844—
ProductHCID 136230232HCID 13623023261.5%

Reaction Steps

The product is prepared according to the procedure described in Example 5, using 250 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 240 mg of 4-fluoro-3-methylaniline in place of the 2,4-difluoroaniline. 204 mg of N-(4-fluoro-3-methylphenyl)-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a white solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791255B2
Source datasetuspto-grants-2014_07
ORD IDord-0e1d1c223d1f4937a6f9d6c9bca30ecb
Source noteuspto-grants-2014_07