HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-m-toluidine → HCID 136230232, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-m-toluidine | HCID 67981 | — |
| Reactant | Sodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetate | HCID 136041844 | — |
| Product | HCID 136230232 | HCID 136230232 | 61.5% |
Reaction Steps
The product is prepared according to the procedure described in Example 5, using 250 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 240 mg of 4-fluoro-3-methylaniline in place of the 2,4-difluoroaniline. 204 mg of N-(4-fluoro-3-methylphenyl)-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a white solid, the characteristics of which are the following:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791255B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-0e1d1c223d1f4937a6f9d6c9bca30ecb |
| Source note | uspto-grants-2014_07 |