HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Difluoromethoxy)aniline → HCID 136352187, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Difluoromethoxy)aniline | HCID 2774110 | — |
| Reactant | Sodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetate | HCID 136041844 | — |
| Product | HCID 136352187 | HCID 136352187 | 46.4% |
Reaction Steps
The product is prepared according to the procedure described in Example 5, using 200 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 520 mg of 3-(difluoromethoxy)aniline in place of the 2,4-difluoroaniline. 135 mg of N-[3-(difluoromethoxy)phenyl]-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a white solid, the characteristics of which are the following:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791255B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-8b4997eb0e12413486aae6c69ae84ed7 |
| Source note | uspto-grants-2014_07 |