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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1631602Generated: November 1, 2026

2-(3-Aminophenoxy)ethan-1-ol → HCID 136352199, compound

https://huagongshe.com/reaction/1631602

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Aminophenoxy)ethan-1-olHCID 3944845—
ReactantSodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetateHCID 136041844—
ProductHCID 136352199HCID 13635219948.3%

Reaction Steps

The product is prepared according to the procedure described in Example 5, using 260 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 294 mg of 2-(3-aminophenoxy)ethanol in place of the 2,4-difluoroaniline. 180 mg of N-[3-(2-hydroxyethoxy)phenyl]-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a pinkish solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791255B2
Source datasetuspto-grants-2014_07
ORD IDord-04d642d455d94e35b2612f44d3af63f3
Source noteuspto-grants-2014_07