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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1631617Generated: November 4, 2026

3-Bromoaniline → N-(3-bromophenyl)-2-[1-methyl-4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide

https://huagongshe.com/reaction/1631617

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromoanilineHCID 11562—
ReactantSodium [1-methyl-4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetateHCID 57523684—
ProductN-(3-bromophenyl)-2-[1-methyl-4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamideHCID 4985392217.2%

Reaction Steps

The product is prepared according to the procedure described in Example 68, using 200 mg of sodium [1-methyl-4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 257 mg of 3-bromoaniline. 51 mg of N-(3-bromophenyl)-2-[1-methyl-4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a white solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791255B2
Source datasetuspto-grants-2014_07
ORD IDord-1f68793024474458a85b2279892c7121
Source noteuspto-grants-2014_07