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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 163170Generated: October 25, 2026

Dimethylformamide → 6-chloro-3-(4-chlorothiophene-2-carbonyl)-5-fluoro-2-oxo-3H-indole-1-carboxamide

https://huagongshe.com/reaction/163170

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant4-Chlorothiophene-2-carboxylic acidHCID 12290695—
Reactant6-Chloro-5-fluoro-2-oxo-1-indolinecarboxamideHCID 13647640—
Product6-chloro-3-(4-chlorothiophene-2-carbonyl)-5-fluoro-2-oxo-3H-indole-1-carboxamideHCID 9885850—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-4ccfe5c41d294da2b99c41cfd5b0eaf0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)