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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 163180Generated: November 4, 2026

Dichloromethane → 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-(2,2,2-trifluoroethyl)-1-naphthalenecarboxamide

https://huagongshe.com/reaction/163180

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantEthanamine, 2,2,2-trifluoro-HCID 9773—
Reactant4-(Dimethylamino)pyridineHCID 14284—
ReactantPropylphosphonic acidHCID 204484—
Reactant4-[5-(3,5-Dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-1-naphthalenecarboxylic acidHCID 58338630—
ReactantMethyl 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-1-naphthalenecarboxylateHCID 58338637—
Product4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-(2,2,2-trifluoroethyl)-1-naphthalenecarboxamideHCID 16220211—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-89f88c4ee5da496b9297a46b7c7358e0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)